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Platycodin 10% 5% Platycodon Extract

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  • Product Description
    • Commodity name: Platycodin 10% 5% Platycodon Extract

    I. Basic Product Information

    Project

    Content

    Product Name

    Platycodon Extract

    English name

    Platycodin

    Source

    The dried root of Platycodon grandiflorus (Jacq.) A.DC., a plant belonging to the genus Platycodon in the family Campanulaceae.

    Active ingredient

    Platycodin

    Product Specifications

    10%; 5%

    Detection method

    UV

    Product characteristics

    Brownish-yellow powder

    Solubility

    Easily soluble in water, methanol, and ethanol; slightly soluble in acetone and ethyl acetate; sparingly soluble in petroleum ether, diethyl ether, and chloroform.

     

    II. Product Introduction

    1. Source

            Platycodin is a substance that... Platycodon grandiflorus, a plant of the genus Platycodon in the family Campanulaceae. Platycodon grandiflorus (Jacq.) A. DC. The dried root of ) is The high-purity monomeric ingredients, derived from refined raw materials, are obtained through processes such as ethanol reflux extraction and purification using macroporous resins, thereby maximizing the preservation of the active ingredients’ structure and efficacy.

    2. Core Efficacy and Applications

    ( 1 Relieves cough and clears phlegm, moistens the lungs and benefits the throat:

    Effects: Stimulates the secretion of mucus in the respiratory tract mucosa, thins phlegm, and promotes its expectoration (with significant expectorant action); inhibits the cough center, relieving dry cough and paroxysmal cough; reduces inflammation of the pharyngeal mucosa and soothes sore throat.

    Applications: Used for excessive phlegm, cough, and throat discomfort caused by colds, coughs, bronchitis, pneumonia, and other conditions; formulated into traditional Chinese medicines for relieving cough and dissolving phlegm (such as Platycodon Decoction, Cough Syrup, and Pharyngitis Tablets); and incorporated as a natural soothing ingredient in lozenges and throat sprays.

    ( 2 Anti-inflammatory and anti-swelling, immune modulation:

    Efficacy: Inhibits inflammatory factors ( TNF- Alpha, IL-6IL-1 β) Release, block inflammatory signaling pathways, and alleviate local tissue inflammation and swelling; regulate the activity of immune cells (macrophages, lymphocytes), thereby enhancing the body’s non-specific immune function.

    Applications: As an adjunct therapy for inflammatory diseases (such as tonsillitis, mumps, and mastitis); for topical care of skin inflammations (such as eczema and acne), helping to relieve redness, swelling, and itching; and as an immune-modulating ingredient added to health supplements to enhance the body’s resistance.

    ( 3 ) Digestive System Protection and Regulation:

    Benefits: Promotes gastrointestinal motility, enhances the secretion of digestive juices, and relieves indigestion and bloating; inhibits damage to the gastric mucosa, promotes its repair, and provides supportive protection for gastric ulcers and gastritis; regulates the balance of intestinal flora and improves the gut microbiome.

    Applications: As an adjunct therapy for chronic gastritis, peptic ulcers, and functional dyspepsia; as a component of traditional Chinese medicine compound formulations aimed at aiding digestion and resolving food stagnation (e.g., Zhi Shi Dao Zhi Wan); and as an ingredient added to gastrointestinal health supplements and functional foods.

    ( 4 ) Cardiovascular protection and other supportive effects:

    Benefits: Dilates blood vessels, improves endothelial function, and helps lower blood pressure; reduces blood viscosity, inhibits platelet aggregation, and decreases the risk of thrombus formation; exhibits mild antioxidant activity, scavenges free radicals, and reduces oxidative damage to cells.

    Applications: Assists in the management of hypertension, hyperlipidemia, and atherosclerosis; added as an antioxidant ingredient to anti-aging skincare products to help repair the skin barrier; in vitro experiments have shown mild inhibitory effects on certain tumor cells, making it a potential ingredient for adjuvant cancer therapy (further clinical validation is required).

    ( 5 ) Traditional Chinese Medicine’s distinctive applications:

    Effects: Traditional Chinese medicine believes that it... “Clears the lungs, regulates qi, and promotes the unobstructed passage of both urine and stool,” which can alleviate chest tightness and abdominal distension caused by stagnation of lung qi, as well as difficulty urinating and constipation.

    Application: Used for TCM syndrome differentiation as Symptoms such as chest tightness, coughing and wheezing, and abdominal distension associated with “lung qi not flowing smoothly”; when combined with other Chinese herbs, it helps regulate the body’s qi flow and address physical heaviness and slowed metabolism caused by stagnation of qi and accumulation of phlegm-dampness.

     

    III. Technical Specifications and Testing Standards

    Testing items

    Testing standards

    Test results

    Detection method

    Specifications

    ≥10.0%

    10.1%

    UV

    Characteristics

    Brownish-yellow powder

    Brownish-yellow powder

    Visual inspection

    Smell

    Unusual odor

    Unusual odor

    Sensory evaluation

    Granularity

    99% passes through an 80-mesh sieve.

    99% passes through an 80-mesh sieve.

    Sift

    Heavy metals

    ≤10 ppm

    <10 ppm

    AAS

    Lead

    ≤2 ppm

    <2 ppm

    AAS

    Arsenic

    ≤2 ppm

    <2 ppm

    AAS

    Moisture

    ≤5.0%

    3.15%

    Constant-temperature drying method

    Ash content

    ≤5.0%

    2.15%

    High-temperature incineration method

    Total colony count

    ≤1000 CFU/g

    30 CFU/g

    Plate Count Method

    Mold yeast

    ≤100 CFU/g

    20 CFU/g

    Plate Count Method

    Escherichia coli

    Not detectable

    Not detectable

    Selective medium method

    Salmonella

    Not detectable

    Not detectable

    Selective enrichment method

     

    IV. Packaging and Storage

    1. Packaging specifications

    ● Small packaging: Sterile aluminum foil pouch (lined with a double-layer polyethylene bag)

    ● Large packaging: 25 kg cardboard drum (lined with double-layer polyethylene bags, drum lid sealed);

    ● Export packaging: Packaging available upon request.

    2. Storage conditions

    ● Storage conditions: Store in a sealed, cool, and dry place (temperature ≤25℃, relative humidity ≤60%), and avoid direct sunlight, high temperatures, and humidity.

    ● Shelf life: 24 months when stored under appropriate conditions and the package remains unopened.

    ● Transportation precautions: Handle with care and avoid crushing or damage; during transportation, protect from sunlight and moisture.

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