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Baicalein 98% Scutellaria Extract

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Application Areas

Pharmaceutical Raw Materials

Reference Substance

Product Series

Plant Monomer Series

Product Type

Natural Active Monomer

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  • Product Description
    • Commodity name: Baicalein 98% Scutellaria Extract

    I. Basic Product Information

    Project

    Content

    Product Name

    Huangqin extract

    English name

    Wogonin

    Source

    The dried root of Scutellaria baicalensis Georgi, a plant of the Lamiaceae family.

    Active ingredient

    Huangqin extract

    CAS No.:

    632-85-9

    Product Specifications

    98%

    Detection method

    HPLC

    Product characteristics

    Yellow needle-shaped crystalline powder

    Solubility

    Soluble in organic solvents, insoluble in water.

     

    II. Product Introduction

    1. Source

            Huangqin素 is a substance that... Scutellaria baicalensis, a plant of the Lamiaceae family. Scutellaria baicalensis Georgi Dried root of ) The highly purified monomeric ingredients, extracted and refined from raw materials, are obtained through processes such as ethanol reflux extraction and purification using macroporous resins, thereby maximizing the preservation of the active ingredients’ structure and efficacy.

    2. Core Efficacy and Applications

    ( 1 ) Anti-inflammatory and antioxidant

    Efficacy: Inhibit TNF- Alpha, IL-6IL-1 beta   Release inflammatory factors and block inflammatory signaling pathways; scavenge free radicals and enhance... SOD GSH-Px Enhance antioxidant enzyme activity and reduce oxidative stress-induced cellular damage.

    Application: Auxiliary treatment for inflammation-related diseases (such as rheumatoid arthritis, colitis, and hepatitis); added to anti-inflammatory and soothing skincare products to reduce inflammatory responses in acne-prone and sensitive skin and to repair the skin barrier.

    ( 2 ) Antitumor activity

    Efficacy: Inhibits tumor cell proliferation, invasion, and metastasis, and induces tumor cell apoptosis; arrests the tumor cell cycle while enhancing the body’s anti-tumor immune function. It exhibits in vitro inhibitory effects on a variety of tumor cells, including those from lung cancer, breast cancer, liver cancer, and colorectal cancer.

    Application: As a raw material for the development of natural anti-tumor candidate drugs, it is used in cancer drug screening and formulation development; it also serves as an adjunctive support following tumor radiotherapy and chemotherapy, reducing damage to normal cells caused by radiation and chemotherapy and enhancing treatment tolerance.

    ( 3 ) Cardiovascular protection

    Efficacy: Dilates blood vessels, improves endothelial function, inhibits platelet aggregation, and reduces the risk of thrombosis; regulates lipid metabolism and alleviates the formation of atherosclerotic plaques; relieves myocardial ischemia-reperfusion injury.

    Application: Auxiliary treatment for cardiovascular diseases such as coronary heart disease, angina pectoris, hyperlipidemia, and atherosclerosis; used as an active ingredient in traditional Chinese medicine compound formulations or health supplements for cardiovascular health maintenance.

    ( 4 ) Neuroprotection

    Efficacy: Inhibits neuronal apoptosis and alleviates brain ischemia, hypoxia, and neuroinflammatory damage; improves cerebral microcirculation, regulates neurotransmitter balance, and exerts a protective effect against cellular damage associated with neurodegenerative disorders.

    Application: Auxiliary intervention for neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease; used as an adjunctive treatment during the recovery phase of ischemic stroke to improve cognitive and motor functions.

    ( 5 ) Antibacterial and antiviral

    Effect: In vitro, it inhibits the growth of bacteria such as Staphylococcus aureus, Escherichia coli, and Helicobacter pylori; it also exhibits a certain inhibitory effect on the replication of viruses including influenza virus, hepatitis B virus, and herpes virus.

    Application: Develop natural antibacterial formulations for topical antibacterial ointments and oral care products; used as an adjunct therapy for Helicobacter pylori infection and viral hepatitis (to be used in combination with conventional medications).

     

    III. Technical Specifications and Testing Standards

    Testing items

    Testing standards

    Test results

    Detection method

    Specifications

    ≥98.0%

    98.1%

    HPLC

    Characteristics

    Yellow needle-shaped crystalline powder

    Yellow needle-shaped crystalline powder

    Visual inspection

    Smell

    Unusual odor

    Unusual odor

    Sensory evaluation

    Granularity

    99% passes through an 80-mesh sieve.

    99% passes through an 80-mesh sieve.

    Sift

    Heavy metals

    ≤10 ppm

    <10 ppm

    AAS

    Lead

    ≤2 ppm

    <2 ppm

    AAS

    Arsenic

    ≤2 ppm

    <2 ppm

    AAS

    Moisture

    ≤3.0%

    0.15%

    Constant-temperature drying method

    Ash content

    ≤3.0%

    0.12%

    High-temperature incineration method

    Total colony count

    ≤1000 CFU/g

    30 CFU/g

    Plate Count Method

    Mold yeast

    ≤100 CFU/g

    20 CFU/g

    Plate Count Method

    Escherichia coli

    Not detectable

    Not detectable

    Selective medium method

    Salmonella

    Not detectable

    Not detectable

    Selective enrichment method

     

    IV. Packaging and Storage

    1. Packaging specifications

    ● Small packaging: Sterile aluminum foil pouch (lined with a double-layer polyethylene bag)

    ● Large packaging: 25 kg cardboard drum (lined with double-layer polyethylene bags, drum lid sealed);

    ● Export packaging: Packaging available upon request.

    2. Storage conditions

    ● Storage conditions: Store in a sealed, cool, and dry place (temperature ≤25℃, relative humidity ≤60%), and avoid direct sunlight, high temperatures, and humidity.

    ● Shelf life: 24 months when stored under appropriate conditions and the package remains unopened.

    ● Transportation precautions: Handle with care and avoid crushing or damage; during transportation, protect from sunlight and moisture.

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