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Glaucine 95% Aconitum Extract

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Reference Substance

Pharmaceutical Raw Materials

Product Series

Plant Monomer Series

Product Type

Natural Active Monomer

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  • Product Description
    • Commodity name: Glaucine 95% Aconitum Extract

    I. Basic Product Information

    Project

    Content

    Product Name

    Gao Wu Jia Su

    English name

    Lappaconitine

    Source

    Aconitum carmichaelii, a perennial herbaceous plant belonging to the genus Aconitum in the family Ranunculaceae.

    Active ingredient

    Gao Wu Jia Su

    CAS No.:

    32854-75-4

    Product Specifications

    95%

    Detection method

    Titration method

    Product characteristics

    White powder

    Solubility

    Soluble in methanol, slightly soluble in water and ethanol, and almost insoluble in chloroform.

     

    II. Product Introduction

    1. Source

            Gao Wu Jia Su is a substance that... Aconitum carmichaelii, a perennial herbaceous plant belonging to the genus Aconitum in the family Ranunculaceae. Aconitum sinomontanum Nakai The highly purified monomeric ingredients, extracted and refined from raw materials, are obtained through processes such as ethanol reflux extraction and purification using macroporous resin, thereby maximizing the preservation of the active ingredients’ structure and efficacy.

    2. Core Efficacy and Applications

    ( 1 ) Potent analgesia: This is a non-addictive analgesic with an analgesic potency comparable to morphine (yet devoid of the addictive properties associated with opioids). It is effective against a variety of pain types and works by blocking sodium ion channels at nerve endings, thereby inhibiting the transmission of pain signals.

    ( 2 Anti-inflammatory and anti-edema: Inhibits the release of inflammatory factors (such as prostaglandins and histamine), reduces local tissue inflammatory responses, and alleviates swelling and pain caused by inflammation (particularly suitable for pain associated with inflammation).

    ( 3 Mild antipyretic effect: Provides a mild cooling effect for patients with fever, helping to relieve discomfort associated with fever. It has a gentle action and carries no significant risk of a sudden drop in body temperature.

    ( 4 Sedative adjunct: Some patients may experience mild sedation after use, which helps alleviate anxiety and irritability associated with pain and enhances pain tolerance.

     

    III. Technical Specifications and Testing Standards

    Testing items

    Testing standards

    Test results

    Detection method

    Specifications

    ≥95.0%

    95.2%

    Titration method

    Characteristics

    White powder

    White powder

    Visual inspection

    Smell

    Unusual odor

    Unusual odor

    Sensory evaluation

    Granularity

    99% passes through an 80-mesh sieve.

    99% passes through an 80-mesh sieve.

    Sift

    Heavy metals

    ≤10 ppm

    <10 ppm

    AAS

    Lead

    ≤2 ppm

    <2 ppm

    AAS

    Arsenic

    ≤2 ppm

    <2 ppm

    AAS

    Moisture

    ≤3.0%

    2.15%

    Constant-temperature drying method

    Ash content

    ≤3.0%

    0.12%

    High-temperature incineration method

    Total colony count

    ≤1000 CFU/g

    30 CFU/g

    Plate Count Method

    Mold yeast

    ≤100 CFU/g

    20 CFU/g

    Plate Count Method

    Escherichia coli

    Not detectable

    Not detectable

    Selective medium method

    Salmonella

    Not detectable

    Not detectable

    Selective enrichment method

     

    IV. Packaging and Storage

    1. Packaging specifications

    ● Small packaging: Sterile aluminum foil pouch (lined with a double-layer polyethylene bag)

    ● Large packaging: 25 kg cardboard drum (lined with double-layer polyethylene bags, drum lid sealed);

    ● Export packaging: Packaging available upon request.

    2. Storage conditions

    ● Storage conditions: Store in a sealed, cool, and dry place (temperature ≤25℃, relative humidity ≤60%), and avoid direct sunlight, high temperatures, and humidity.

    ● Shelf life: 24 months when stored under appropriate conditions and the package remains unopened.

    ● Transportation precautions: Handle with care and avoid crushing or damage; during transportation, protect from sunlight and moisture.

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